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Article Details

  • Article Code : FIRAT-AKADEMI-7676-5587
  • Article Type : Araştırma Makalesi
  • Publication Number : 3A0097
  • Page Number : 1-16
  • Doi : 10.12739/NWSA.2023.18.1.3A0097
  • Abstract Reading : 251
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Issue Details

  • Year : 2023
  • Volume : 18
  • Issue : 1
  • Number of Articles Published : 1
  • Published Date : 1.01.2023

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Physical Sciences

Serial Number : 3A
ISSN No. : 1308-7304
Release Interval (in a Year) : 4 Issues

STUDY OF SERUM GHRELIN LEVEL IN PATIENTS WITH DIABETES MELLITUS TYPE 2: IN RELATION WITH INSULIN LEVEL

Aysel SARI1 , Zhiyan Muhammed Shaker Ahmed2

Ghrelin is an orexigenic hormone. It has a suppressive effect on insulin release from pancreatic islets. In T2DM patients, hyperinsulinemia, lower ghrelin levels are observed. Total ghrelin levels in fasting plasma were lower in T2DM patients than in non-diabetic patients. It was aimed to consider serum ghrelin windows in the T2DM patient and control. It was observed that ghrelin diabetes experiments in general patient groups were estimated to be lower (262.37±129.29pg/mL), (487.40±53.81pg/mL) compared to the control group (p<0.001). Patient group insulin (27.39±11.06µU/mL) and control settings (12.07±5.49µU/mL) (p<0.001). It also shows high yield positive rates with ghrelin and insulin history (p<0.001, r=-0.699). Significantly improved performance with serum ghrelin and insulin, culprit glucose and HbA1C. A significant relationship between ghrelin and insulin and T2DM has been investigated in this comprehensive context, and there is a content relationship between ghrelin and insulin.

Keywords
Ghrelin, Insulin, Type 2 Diabetes, Plasma, Serum,

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Authors

Aysel SARI (1) (Corresponding Author)

Fırat Üniversitesi
ayselsari@hotmail.com | 0000-0002-4966-2254

Zhiyan Muhammed Shaker Ahmed (2)

Duhok specialized center for laboratory
zhiyanakreyi@yahoo.com | 0000-0003-0668-2316

Supporting Institution

:

Project Number

:

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