THE EFFECTS OF ENDOCRINE DISRUPTORS ON SOME VERTEBRATES

Özlem ÖNEN¹ , PINAR AKSU KILIÇLE²

The studies about the histological effects of endocrine disruptor chemicals on vertebrates were presented and evaluated, and it was aimed to be summarized in such a way that it can generate resources for future studies. The available literatural information was arranged as review by revising in the direction of the researches in Kafkas University, Faculty of Arts and Sciences, Department of Biology Laboratories. Although the endocrine disruptor chemicals presence is tried to be limited at the ecosystem level, the extensive usage of this chemicals in various areas still continues. Many organisms are directly or indirectly exposed to the adverse effects of endocrine disruptor chemicals in this direction. In this review, histological changes occurring in vertebrates as a result of exposure to endocrine disruptor chemicals were investigated. It has been reported that different endocrine disruptor chemical types cause similar histopathological findings in vertebrates in the data obtained from investigations. In the context of the examined data, the effects of endocrine disruptors on some tissues seem to be more variable. Histopathology is a useful tool in endocrine disruptor studies and may provide information on the mechanism of endocrine disruptors that is sometimes unexpected.

Keywords
Endocrine Disruptors, Toxication, Histopathology, Vertebrates, Biology, Hormone,